Topiramate (Topamax) Mega Study
Topiramate (Topamax)
Topiramate (Topamax)





Treatment Effectiveness

User reported effectiveness ratings Topiramate (Topamax) for various conditions.

Conditions Major Improvement Moderate Improvement Much Worse No Effect Worse Responses
Migraine 12% 28% 12% 40% 7% 572
Peripheral Neuropathy 0% 50% 50% 0% 0% 2

Side Effects

User-reported side effects of Topiramate (Topamax)

Side Effect Percent of Reports Topiramate (Topamax)
Irritability 41%
Nervousness 29%
Diarrhea 14%
Constipation 21%
Dandruff 10%
Depression 34%
Dry Mouth 36%
Heartburn 12%
Aggressive Behavior 18%
Back, Muscle, or Bone Pain 21%
Bruised Feeling When Skin Is Touched 0%
Change in Ability to Taste Food 28%
Confusion 42%
Difficulty Concentrating 70%
Difficulty Falling or Staying Asleep 27%
Difficulty Urinating or Pain When Urinating 6%
Drowsiness 43%
Excessive Menstrual Bleeding 5%
Excessive Movement 8%
Extreme Thirst 26%
Facial Numbness 13%
Growth of Hair in Unusual Places 1%
Hair Loss 17%
Hypersensitive Tastebuds 0%
Increased Saliva 3%
Joint Aches 16%
Lack of Coordination 41%
Memory Problems 66%
Missed Menstrual Periods 5%
Mood Swings 38%
Narrow Angle Glaucoma 0%
Nosebleed 5%
Numbness, Burning, or Tingling in the Hands or Feet 52%
Overgrowth of the Gums 1%
Ringing in the Ears 22%
Short-Term Memory Loss 31%
Skin Problems or Changes in Skin Color 5%
Slowed Reactions 59%
Some Foods Smelled and Tasted Rotten 13%
Speech Problems, Especially Difficulty Thinking of Specific Words 69%
Supposed to Be Under Tramadol---Makes Be Depressive 4%
Swelling of the Hands, Arms, Feet, Ankles, or Lower Legs 10%
Swelling of the Tongue 1%
Teary or Dry Eyes 19%
Trouble Swallowing 7%
Uncontrollable Eye Movements 6%
Uncontrollable Shaking of a Part of the Body 12%
Very Heavy Periods That Lasted for 3 or 4 Weeks When I Was in My 20s 2%
Vomiting 4%
Weakness 32%
Weight Loss 35%
Headache 35%
Gas 14%
Joint Pain 7%

Below is the degree of change seen after Topiramate (Topamax) is higher than average.

Below is the change in the listed outcome after is higher than average.
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% Change from Baseline*
Change in the listed outcome after is higher than average.

Topiramate (Topamax) Info

Property Value
Variable Name Topiramate (Topamax)
Aggregation Method SUM
Analysis Performed At 2020-04-03
Duration of Action 21 days
Filling Value 0
Minimum Allowed Value 0 count
Number of Aggregate Predictors 0
Number of Aggregate Outcomes 0
Number of Measurements 0
Number of Measurements (including those generated by tagged, joined, or child variables) 0
Public true
Onset Delay 30 minutes
Unit Count
User Variables 0
Variable Category Treatments
Variable ID 95602